Obesity Research

Obesity Research

The mainstream idea that the causes of obesity are rooted in a lack of exercise and overeating are simplistic and evidentially incorrect. People do eat less and exercise more, and yet obesity rates are climbing. The research which highlights the safety, indeed the necessity in some cases, and the efficacy of carbohydrate restriction on obesity rates can no longer be denied or ignored.

Section Links: 2011 | 2010 | 2009 | 2008 | 2007 and older

2011

• Change in Food Cravings, Food Preferences, and Appetite During a Low-Carbohydrate and Low-Fat Diet. Corby K. Martin, Diane Rosenbaum, Hongmei Han, Paula J. Geiselman1, Holly R. Wyatt, James O. Hill, Carrie Brill, Brooke Bailer, Bernard V. Miller III, Rick Stein, Sam Klein and Gary D. Foster
• Low-Carbohydrate Diet Review: Shifting the Paradigm. Adele H. Hite,
  Valerie Goldstein Berkowitz and Keith Berkowitz
• High-protein low-carbohydrate diets: what is the rationale? Luca Busetto, Mariangela Marangon, Fabio De Stefano
• The effects of high-protein, low-carbohydrate diet on body weight and the expression of gastrointestinal hormones in diet-induced obesity rat. Chen HY, Ma LC, Li YY, Zhao JJ, Li ML

2010

• The effect of low-carbohydrate diet on left ventricular diastolic function in obese children. Cenap Zeybek, Ahmet Celebi, Cigdem Aktuglu-Zeybek, Hasan Onal, Yalim Yalcin, Abdullah Erdem, Celal Akdeniz, Elnur Imanov, Suheyla Altay, Ahmet Ayd?n
• Weight and Metabolic Outcomes After 2 Years on a Low-Carbohydrate Versus Low-Fat Diet. Gary D. Foster, PhD; Holly R. Wyatt, MD; James O. Hill, PhD; Angela P. Makris, PhD, RD; Diane L. Rosenbaum, BA; Carrie Brill, BS; Richard I. Stein, PhD; B. Selma Mohammed, MD, PhD; Bernard Miller, MD; Daniel J. Rader, MD; Babette Zemel, PhD;
  Thomas A. Wadden, PhD; Thomas Tenhave, PhD; Craig W. Newcomb, MS; and Samuel Klein, MD
• Low-carbohydrate ketogenic diet and the combination of orlistat with a low-fat diet lead to comparable improvements in weight and blood lipids, but LCKD more beneficial for blood pressure. Christopher D Gardner
• The Eat Smart Study: A randomised controlled trial of a reduced carbohydrate versus a low fat diet for weight loss in obese adolescents. Helen Truby, Kimberley A Baxter, Paula Barrett, Robert S Ware, John C Cardinal, Peter SW Davies,
  Lynne A Daniels, Jennifer A Batch
• Resistance training in overweight women on a ketogenic diet conserved lean body mass while reducing body fat. Pal T Jabekk1, Ingvild A Moe, Helge D Meen, Sissel E Tomten, Arne T Høstmark
• Short term effects of a low-carbohydrate diet in overweight and obese subjects with low HDL-C levels. Ahmet Selçuk Can, Canan Uysal, K Erhan Palaog(lu
• Comparison of anthropometric and metabolic responses to a short-term carbohydrate restricted diet and exercise versus a traditional diet and exercise. GA Brown, AM Swendener, BS Shaw, I Shaw
• Renal Function Following Long-Term Weight Loss in Individuals with Abdominal Obesity on a Very-Low-Carbohydrate Diet vs High-Carbohydrate Diet. Brinkworth, PhD, Jonathan D. Buckley, PhD, Manny Noakes, PhD, Peter M. Clifton, PhD
• Low-Carbohydrate Diets Promote a More Favorable Body Composition Than Low-Fat Diets. Volek, Jeff S PhD, RD; Quann, Erin E PhD, RD; Forsythe, Cassandra E PhD, RD

2009

• Systematic review of randomized controlled trials of low-carbohydrate vs. low-fat/low-calorie diets in the management of obesity and its comorbidities. M. Hession, C. Rolland, U. Kulkarni, A. Wise, J. Broom
• A low carbohydrate Mediterranean diet improves cardiovascular risk factors and diabetes control among overweight patients with type 2 diabetes mellitus: a 1-year prospective randomized intervention study. A. Elhayany, A. Lustman2,3, R. Abel, J. Attal-Singer and S. Vinker
• Long-term effects of a very-low-carbohydrate weight loss diet compared with an isocaloric low-fat diet after 12 months. Grant D Brinkworth, Manny Noakes, Jonathan D Buckley, Jennifer B Keogh, and Peter M Clifton
• Comparative Study of the Effects of a 1-Year Dietary Intervention of a Low-Carbohydrate Diet Versus a Low-Fat Diet on Weight and Glycemic Control in Type 2 Diabetes. Nichola J. Davis, MD, MS, Nora Tomuta, MD, Clyde Schechter, MD, Carmen R. Isasi, MD, PHD, C.J. Segal-Isaacson, EDD, RD, Daniel Stein, MD, Joel Zonszein, MD and Judith Wylie-Rosett, EDD, RD
• A 6-Month, Office-Based, Low-Carbohydrate Diet Intervention in Obese Teens.
  Robert M. Siegel, MD, Whitney Rich, RD, Evelyn C. Joseph, MD, Joan Linhardt, Jamie Knight, Jane Khoury, PhD, Stephen R. Daniels, MD, PhD
• Low-carbohydrate diets: An update on current research. Judith Wylie-Rosett and Nichola J. Davis
• Right Ventricular Subclinical Diastolic Dysfunction in Obese Children: The Effect of Weight Reduction with a Low-Carbohydrate Diet. Cenap Zeybek, Cigdem Aktuglu-Zeybek, Hasan Onal, Süheyla Altay, Abdullah Erdem and Ahmet Celebi
• Long-term effects of a low carbohydrate, low fat or high unsaturated fat diet compared to a no-intervention control. S.S. Lim, M. Noakes, J.B. Keogh, P.M. Clifton
• Carbohydrate Restriction, as a First-Line Dietary Intervention, Effectively Reduces Biomarkers of Metabolic Syndrome in Emirati Adults. Taif Al-Sarraj, Hussein Saadi, Mariana C. Calle, Jeff S. Volek, and Maria Luz Fernandez
• White Tea extract induces lipolytic activity and inhibits adipogenesis in human subcutaneous (pre)-adipocytes Jörn Söhle, Anja Knott, Ursula Holtzmann, Ralf Siegner, Elke Grönniger, Andreas Schepky, Stefan Gallinat, Horst Wenck, Franz Stäband Marc Winnefeld

2008

• Weight Loss With a Low-Carbohydrate, Mediterranean, or Low-Fat Diet. Shai, Iris; Schwarzfuchs, Dan; Henkin, Yaakov; Shahar, Danit R.; Witkow, Shula; Greenberg, Ilana; Golan, Rachel; Fraser, Drora; Bolotin, Arkady; Vardi, Hilel; Tangi-Rozental, Osnat; Zuk-Ramot, Rachel; Sarusi, Benjamin; Brickner, Dov; Schwartz, Ziva; Sheiner, Einat; Marko, Rachel; Katorza, Esther; Thiery, Joachim; Fiedler, Georg Martin; Blüher, Matthias; Stumvoll, Michael; Stampfer, Meir J.; for the Dietary Intervention Randomized Controlled Trial (DIRECT) Group
• Systematic review of randomized controlled trials of low-carbohydrate vs. low-fat/low-calorie diets in the management of obesity and its comorbidities. M. Hession, C. Rolland, U. Kulkarni, A. Wise, J. Broom
• Effects of weight loss from a very-low-carbohydrate diet on endothelial function and markers of cardiovascular disease risk in subjects with abdominal obesity. Jennifer B Keogh, Grant D Brinkworth, Manny Noakes, Damien P Belobrajdic, Jonathan D Buckley, and Peter M Clifton
• Orlistat inhibition of intestinal lipase acutely increases appetite and attenuates postprandial glucagon PubMed (Abstract), October 2008
• The joint impact on being overweight of self reported behaviours of eating quickly and eating until full: cross sectional survey BMJ 2008;337:a2002
• Weight Loss on a Low Carbohydrate, Mediterreanean or Low Fat Diet NEJM July 17, 2008

2007 and older

• The effects of low-carbohydrate versus conventional weight loss diets in severely obese adults: one-year follow-up of a randomized trial. Ann Intern Med 2004;140:778-85. Stern L, et al.
• Randomized Trial of a Low-Carbohydrate Diet for Obesity New England Journal of Medicine
• Fatness, Fitness, and Insulin Sensitivity Among 7- to 9-Year-Old Children Joey C. Eisenmann, Katrina D. DuBose and Joseph E. Donnelly The purpose of this study was to examine the relationships among fatness and aerobic fitness on indices of insulin resistance and sensitivity in children.
• Minimal versus Umbilical Waist Circumference Measures as Indicators of Cardiovascular Disease We examined two WC locations to determine which was more highly correlated with CVD risk factors and metabolic syndrome (MS).
• Effect of Weight Loss on Predicted Cardiovascular Risk: Change in Cardiac Risk After Bariatric Surgery. Our goal was to assess the effect of bariatric surgery on cardiovascular risk estimations of preventable, long-term adverse outcomes.
• Associations Between the Home Food Environment and Obesity-promoting Eating Behaviors in Adolescence This study examines relationships between multiple aspects of the home food environment and obesity-promoting characteristics of 12- to 13-year-old adolescents’ diets, specifically frequency of consumption of high-energy fluids, sweet snacks, savory snacks, and take-out foods.
• Measures of Adiposity and Cardiovascular Disease Risk Factors Study to determine which of five measures of adiposity maintains the strongest association with cardiovascular disease risk factors.
• The relation of gender, race and socioeconomic status to obesity and obesity comorbidities in a sample of US adults Examination of the obesity-related chronic diseases in the US adult population according to gender, race and socioeconomic status.